Maricopa Community Colleges  BIO241   19982-99999 
Official Course Description: MCCCD Approval: 05/27/97
BIO241 19982-99999 LEC
LAB 		4 Credit(s)
0 Credit(s) 		3 Period(s)
3 Period(s)
Human Genetics
An introduction to the basic concepts of human heredity and cytogenetics including Mendelian, molecular, and population genetics. Prerequisites: BIO100, or BIO181, or equivalent, or permission of instructor.
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MCCCD Official Course Competencies:
 
BIO241   19982-99999 Human Genetics
1. Describe the major contributions to the development of human genetics. (I)
2. Define terms used inhuman genetics. (II)
3. Contrast between the major modes of monogenic inheritance. (III)
4. Describe the mechanics of cell division. (IV)
5. Describe the biochemical nature of genes and chromosomes. (IV)
6. Describe recombinant DNA technology. (IV)
7. Describe how numerical and structural chromosome abnormalities arise. (IV)
8. Describe the nature and causes of mutation. (IV)
9. Describe the basic tenets of multigenic inheritance. (V)
10. Describe the underlying principles of population genetics. (VI)
11. Describe the importance of prenatal diagnostic techniques in genetic counseling. (VII)
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MCCCD Official Course Outline:
 
BIO241   19982-99999 Human Genetics
    I. History of the Development of Human Genetics
      II. Terminology of Human Genetics
        III. Principles of Mendelian Genetics
            A. Autosomal recessive
            B. Autosomal dominant
            C. X-linked recessive
            D. X-linked dominant
            E. Y-linked
          IV. Chromosomes and Genes
              A. Physical basis of inheritance
              B. Chemical nature of genes and chromosomes
                1. Replication, transcription, and translation
                2. Recombinant DNA technology
              C. Mitosis
              D. Meiosis and gamete formation
              E. Gene mapping
              F. Expression of genes and regulation of expression
              G. Numerical chromosomal abnormalities
              H. Structural chromosomal abnormalities
              I. Mutation
              J. Karyotyping
              K. Biochemical genetics
                1. Metabolic disorders
                2. Amniocentesi: screen for enzymes
              L. Genetics of the immune system
                1. Blood groups
                2. Histocompatibility and the HLA system
                3. Antibody formation
                4. Autoimmune disorders
            V. Polygenic Traits
              VI. Genes in Populations
                  A. Gene frequencies
                  B. Genotype frequencies
                  C. Calculation of gene frequencies
                  D. Hardy-Weinburg equilibrium
                VII. Availability of Prenatal Diagnostic Techniques
                    A. Amniocentesis
                    B. Chorionic villi analysis
                    C. Use of DNA probes
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